GlyTouCan version 1.0 was released in 2015 as the international glycan structure repository, and a new sequence format called WURCS (Web3 Unique Representation of Carbohydrate Structures) was proposed during the early stages of the GlyTouCan project. GlyTouCan uses WURCS as its base representation for glycans because existing formats were insufficient in their flexibility to represent any and all glycans universally. Therefore, in order to obtain WURCS strings for existing or new glycan structures, conversion tools or glycan structure editors that can export WURCS became necessary. GlycanBuilder was an obvious choice to extend due to its wide usage by the community. However, GlycanBuilder was limited because it was originally developed to support mammalian glycans. It also did not support the newly proposed monosaccharide symbol standard called Symbol Nomenclature for Glycans (SNFG). Therefore in this work, we implemented a new version of GlycanBuilder to greatly increase its usability. The glycan rendering system was refactored so that cyclic glycans, nested repeating units, monosaccharide compositions and cross-linked glycan structures can be represented. Both import and export utilities for WURCS were also implemented and SNFG symbols were incorporated to allow glycans to be exported as graphics using the latest glycan symbol nomenclature. This new version of GlycanBuilder called "GlycanBuilder2", is able to support a wide variety of ambiguous glycans, including structures containing monosaccharides from bacteria and plants. These glycans can also be displayed using the new SNFG symbols. This tool can aid researchers in communicating about the complex, diverse, and ambiguous structures of glycans more rapidly. Moreover, the new GlycanBuilder can now easily output WURCS sequences from glycans drawn on the canvas. Most importantly, because GlyTouCan employs WURCS as the basic format for registration and searching of glycan information, a wider variety of glycans can now be readily registered and queried in GlyTouCan.
Distributed ledger technology, a method of storing and maintaining the integrity of multiple copies of critical data using a massively redundant network of participating machines, has found a “killer application” in blockchain, a type of distributed ledger. A blockchain consists of sequential blocks that may never be modified or reordered, leaving a public, auditable record that is consistent and highly resistant to tampering and deletion. These qualities make blockchain eminently suitable for its most common use, cryptocurrency, and its occasional variants in the form of cryptocurrency tokens, used to represent ownership or some other right to virtual or physical goods and capabilities. Blockchain also enables smart contracts, discrete bodies of software written to serve both as the memorial and the means of execution of an agreement between parties. Smart contracts can have all the elements of a traditional contract, and as jurisdictions legislate or jurists rule on the fine points of enforceability and the acceptability of smart contracts as traditional contracts, applications in nearly every area of commerce have emerged. Digital lawyers may not need to become software developers, but deepening their understanding of the capabilities and limitations of the technology, developing a keen awareness of the issues at the intersection between code and the law, as well as the law’s readiness in this area, will be of great advantage to them and their clients in this rapidly evolving area at the intersection of technology, commerce and law.
Masaaki Matsubara, Kiyoko F. Aoki‐Kinoshita, Nobuyuki P. Aoki, Issaku Yamada · 5 authors
Accurate representation of structural ambiguity is important for storing carbohydrate structures containing varying levels of ambiguity in the literature and databases. Although many representations for carbohydrates have been developed in the past, a generalized but discrete representation format did not exist. We had previously developed the Web3 Unique Representation of Carbohydrate Structures (WURCS) in an attempt to define a generalizable and unique linear representation for carbohydrate structures. However, it lacked sufficient rules to uniquely describe ambiguous structures. In this work, we updated WURCS to handle such ambiguous monosaccharide structures. In particular, to handle structural ambiguity around (potential) carbonyl groups incidental to the carbohydrate analysis, we defined a representation of backbone carbons containing atomic-level ambiguity. As a result, we show that WURCS 2.0 can represent a wider variety of carbohydrate structures containing ambiguous monosaccharides, such as those whose ring closure is undefined or whose anomeric information is only known. This new format provides a representation of carbohydrates that was not possible before, and it is currently being used by the International Glycan Structure Repository GlyTouCan.
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Ubiquitous sensing enabled by Wireless Sensor Network (WSN) technologies cuts across many areas of modern day living. This offers the ability to measure, infer and understand environmental indicators, from delicate ecologies and natural resources to urban environments. The proliferation of these devices in a communicating-actuating network creates the Internet of Things (IoT), wherein, sensors and actuators blend seamlessly with the environment around us, and the information is shared across platforms in order to develop a common operating picture (COP). Fuelled by the recent adaptation of a variety of enabling wireless technologies such as RFID tags and embedded sensor and actuator nodes, the IoT has stepped out of its infancy and is the the next revolutionary technology in transforming the Internet into a fully integrated Future Internet. As we move from www (static pages web) to web2 (social networking web) to web3 (ubiquitous computing web), the need for data-on-demand using sophisticated intuitive queries increases significantly. This paper presents a Cloud centric vision for worldwide implementation of Internet of Things. The key enabling technologies and application domains that are likely to drive IoT research in the near future are discussed. A Cloud implementation using Aneka, which is based on interaction of private and public Clouds is presented. We conclude our IoT vision by expanding on the need for convergence of WSN, the Internet and distributed computing directed at technological research community.
Die Möglichkeit der Programmierbarkeit des Bitcoins ist fast ein nachträglicher Einfall, auch wenn Sidechain‐Vorschläge diese Programmierbarkeit ein wenig leichter machen wollen und es bereits Altcoins mit verschiedenen spezifischen Anwendungen gibt. Im Gegensatz dazu wurde das Kryptowährungstechnologieprojekt Ethereum von Vitalik Buterin, seinem Erfinder, von Tag 1 als Software‐Entwicklungsplattform für dezentrale Applikationen konzipiert, und ihre Blockchain wurde speziell entwickelt, um die Ausführung dieser dezentralen Apps (auch Dapps genannt) zu unterstützen. Vitalik Buterin, 1994 in Russland geboren, war vor der Gründung von Ethereum auch involviert in die Entwicklungsprojekte Colored Coins und Mastercoins. Er gewann 2014 den "World Technology Award" und ein Stipendium des Risikokapitalgebers Peter Thiel. In dem Diskussionspapier zu Ethereum skizzierte Buterin vor allem die Grenzen einer Programmierbarkeit der Bitcoin‐Blockchain und schlug die Erstellung einer neuen komplett programmierbaren Blockchain mit einer turing‐vollständigen Programmiersprache vor. Anders als andere Blockchain‐Projekte soll die Ethereum Software nicht nur für einen Zweck nutzbar sein – sondern soll die Basis für die Erarbeitung aller möglichen Arten von Lösungen sein und dabei die Umsetzung intelligenter Verträge (Smart Contracts) ebenso erfassen als auch die Ethereum‐spezifische Idee von dezentralen autonomen Organisationen (DAOs).
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Dappfort is a blockchain-focused Web3 development company that helps businesses harness the power of decentralized technologies to build secure, scalable, and future-ready digital solutions. Headquartered in Madurai, India, with additional presence in London, Dappfort works across a broad range of industries — including finance, healthcare, gaming, retail, and supply chain — delivering tailored blockchain and Web3 applications to startups, enterprises, and global organizations. The company’s core services include the design and development of decentralized applications (DApps), crypto exchanges (centralized and decentralized), crypto wallets, NFT marketplaces, DeFi platforms, token creation, smart contract development, and enterprise Web3 integration. Dappfort also expands into related areas such as Web3 e-commerce, AI-powered blockchain solutions, and metaverse experiences, supporting clients from strategy and consulting through deployment and ongoing support. With expertise in major blockchain networks like Ethereum, Solana, Binance Smart Chain, and others, Dappfort positions itself as a full-stack partner for businesses aiming to enter or grow in the decentralized digital economy. While the company promotes a strong innovation- and security-oriented approach, external reviews on third-party platforms show mixed feedback from users about project delivery and quality.
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Introduction au numéro de COMMUNICATION & MANAGEMENT faisant suite au colloque de novembre 2013 du Lerass-Ceric, à Montpellier 3, intitulé : « La culture en projets, service et/ou industrie : d’Adorno au Web3 ». Le texte situe la question théorique des industries culturelles et aborde des aspects problématisés des nouvelles conditions de présence et de développement de la création, notamment en arts plastiques, dans une période qui sollicite autrement les acteurs des industries créatives.
In recent years, the Semantic Web has become the focus of life science database development as a means to link life science data in an effective and efficient manner. In order for carbohydrate data to be applied to this new technology, there are two requirements for carbohydrate data representations: (1) a linear notation which can be used as a URI (Uniform Resource Identifier) if needed and (2) a unique notation such that any published glycan structure can be represented distinctively. This latter requirement includes the possible representation of nonstandard monosaccharide units as a part of the glycan structure, as well as compositions, repeating units, and ambiguous structures where linkages/linkage positions are unidentified. Therefore, we have developed the Web3 Unique Representation of Carbohydrate Structures (WURCS) as a new linear notation for representing carbohydrates for the Semantic Web.
Are there differences between the sale of an unopened Super Mario Bros. computer game and of the digital collage of 5,000 images? Viewed from the perspective of the doctrine of exhaustion, we can easily conclude that the two transfers have significant differences. The auction of the tangible data carrier of the Super Mario’s 1986 edition (for $660,000) 1 fits well into the doctrine. The auction of the NFT (non-fungible token) representing Beeple’s “Everdays: the First 5000 Days” (for an equivalent of an astounding $69.3 million) 2 seems to be hype with a snowball effect rather than a modern encapsulation of digital exhaustion. Some commentators, 3 including the present author in collaboration with Alexandra Giannapoulou, João Pedro Quintais, and Balázs Bodó, 4 have thoroughly introduced the incompatibility of the NFT mania with the existing copyright status quo, and so – in connection with the present book’s topic – the sale of tokenized information, which is capable of representing information related to digital artworks, is practically excluded from the scope of the exhaustion of the right of distribution. At the same time, NFTs de facto offer a “code-based digital ecosystem that has practical consequences for the copyright-relevant fields of creativeness.” 5 The sale and resale of NFTs is possible; an exchange of information and title to “own” and “trade” information related to copyrightable subject matter is technologically guaranteed. In line with that, a quasi-exhaustion regime has also emerged. As such, the NFT mania can practically evidence the need for and modern technology’s capability of offering digital marketplaces for artworks as well.
Web2 and the evolving vision of Web3 have a great effect on facilitation of information sharing, information aggregation, interoperability, user-centered design, collaboration on the World Wide Web, and crowd-centered services. New concept of Web is the intuition that drives crowdsourcing, crowd servicing, and crowd computing. With crowdsourcing emergence people get motivated to work through internet without being limited by time or geographical location. On the other hand employers could have their jobs done faster and cheaper. This paper is going to introduce an innovative approach for Amazon Mechanical Turk (AMT) crowdsourcing marketplace. In current AMT marketplace, workers especially new ones need to qualify themselves for each requester that has submitted Human Intelligence Tasks (HITs) in AMT, and there is lack of shared reputation system; some workers may cheat on tasks in order to maximize their income, as a result requesters are uncertain of the quality of results, so they offer lower rewards and consequently qualified workers leave the marketplace.
Ubiquitous sensing enabled by Wireless Sensor Network (WSN) technologies cuts across many areas of modern day living. This offers the ability to measure, infer and understand environmental indicators, from delicate ecologies and natural resources to urban environments. The proliferation of these devices in a communicating-actuating network creates the Internet of Things (IoT), wherein, sensors and actuators blend seamlessly with the environment around us, and the information is shared across platforms in order to develop a common operating picture (COP). Fuelled by the recent adaptation of a variety of enabling device technologies such as RFID tags and readers, near field communication (NFC) devices and embedded sensor and actuator nodes, the IoT has stepped out of its infancy and is the the next revolutionary technology in transforming the Internet into a fully integrated Future Internet. As we move from www (static pages web) to web2 (social networking web) to web3 (ubiquitous computing web), the need for data-on-demand using sophisticated intuitive queries increases significantly. This paper presents a cloud centric vision for worldwide implementation of Internet of Things. The key enabling technologies and application domains that are likely to drive IoT research in the near future are discussed. A cloud implementation using Aneka, which is based on interaction of private and public clouds is presented. We conclude our IoT vision by expanding on the need for convergence of WSN, the Internet and distributed computing directed at technological research community.
Ubiquitous sensing enabled by Wireless Sensor Network (WSN) technologies cuts\nacross many areas of modern day living. This offers the ability to measure,\ninfer and understand environmental indicators, from delicate ecologies and\nnatural resources to urban environments. The proliferation of these devices in\na communicating-actuating network creates the Internet of Things (IoT),\nwherein, sensors and actuators blend seamlessly with the environment around us,\nand the information is shared across platforms in order to develop a common\noperating picture (COP). Fuelled by the recent adaptation of a variety of\nenabling device technologies such as RFID tags and readers, near field\ncommunication (NFC) devices and embedded sensor and actuator nodes, the IoT has\nstepped out of its infancy and is the the next revolutionary technology in\ntransforming the Internet into a fully integrated Future Internet. As we move\nfrom www (static pages web) to web2 (social networking web) to web3 (ubiquitous\ncomputing web), the need for data-on-demand using sophisticated intuitive\nqueries increases significantly. This paper presents a cloud centric vision for\nworldwide implementation of Internet of Things. The key enabling technologies\nand application domains that are likely to drive IoT research in the near\nfuture are discussed. A cloud implementation using Aneka, which is based on\ninteraction of private and public clouds is presented. We conclude our IoT\nvision by expanding on the need for convergence of WSN, the Internet and\ndistributed computing directed at technological research community.\n
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This paper is focused on the role of main social activities, as creating and sharing personal content. The reason is connected to the raise up, in last ten years, of User Generated Content as a system to allow people to be active on the Web3. In the first paragraph I analyze the Web-population through recent surveys, showing different ways to classify generations. I comment the Jenkins’ “convergence culture” [2006], the push and pull media definition of Negroponte [1995] and the difference between digital natives and digital immigrants [Prensky 2001]. The second paragraph deals with use and consumption of digital media between young and adults from the computer use to mobile-phone and portable gaming device. In particular the mobile-phone seems to be an important medium to be online in every place and every time: it allows people to take and share photos, video, text and so on. This brings us to the third paragraph where I discuss mobility and applications: following Anderson [2010] the desktop is replaced with the webtop or web-applications that do not require a browser to be used. This is particularly evident for recent mobile devices as iPhone and iPad. Convergence and mobility allow people to share content in every time: yet ten years ago people used to share digital information (file-sharing) as video, music and text, by illegal channels such as Napster, without knowing who uploaded that on the Web. The Web 1.0 phase was characterized by an “anonymous dimension”. Instead, the current Web allows people to share information about their own life, publishing on social media, freely, their own photo, video, text, with real name and surname (life-sharing). At the center of the Web is the “ego”, the user. In the fifth chapter I analyze three social media that are currently catching up people’s attention Facebook, YouTube, Twitter – and I try to explain how they make possible to users to share culture and frame of their life. At the end I spent some words about piracy and privacy issue that social media bring up.
Helen Williams of the London School of Economics attended the recent Talis open day covering all things semantic and how to apply these tools and structures in a library setting. Helen has included links to all the presentations from the day that covered a wide range of topics from making library resources web3 ready and the frameworks and schemas used in the Linked Data movement.
In the years following 2008, developing countries as a whole may invest as much as US$100 billion annually in information infrastructure (Khalil & Kenny, 2008). In addition, the rapid expansion of mobile phones—even in the poorer regions of the world1,2—and the emergence of the “social” (i.e., participatory and collaborative) Web3 are rapidly reshaping not only the ways people access and share information, but also how they relate, collaborate, and organize (Benkler, 2006; Shirky, 2008). These new tech-nologies, most notably information and communication technologies (ICTs), offer new and transformative applications and services, means to communicate and produce content, and decentralized innovation models (Heeks, 2008). In this context of expanding ICT networks and applica-tions, Khalil and Kenny (2008) appropriately ask, “How can we catalyze the impact of ICTs on development?” The hypothesis of this paper is that open social arrangements, enabled by ICTs, can help to catalyze the development impacts of ICTs. In other
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The cipher (or athbash, under which name Web3 defines it) is a Hebrew substitution cipher which replaces the first letter of the Hebrew alphabet (aleph, 1\) by the last (tav, ) the second (beth, J) by the last but one (shin, IJI), and so on, unti I we get to the last (ta , n), which i replaced by the first (aleph, 1\). Jan Anderson described it in Fledge Ledge Edge (WW 8. 1997229). Naturally, the idea can be applied to our alphabet; following the precedent set by atbash I name it the azby cipher.