The Internet of Things (IoT) security landscape requires the architectural solutions that can address the technical and operational challenges across the heterogeneous environments. The IoT systems operate in different conditions, and security issues continue to increase. This paper presents the comprehensive security framework for IoT that should integrate the Trusted Execution Environments (TEEs) with the semantic middleware and blockchain technologies. The work provides a systematic analysis of the architectural patterns based on more than twenty recent research works and the existing standards, and it proposes a layered security architecture. The architecture includes the hardware rooted trust at peripheral level, the zero trust principles at network level, and the semantic security mechanisms at application level. The framework focuses on practical implementation aspects such as the performance overhead, interoperability requirements, and the compliance with new regulations, which are very important for the real IoT deployments. The paper reports quantitative metrics which include the cryptographic performance on Cortex-M class microcontrollers with the detection accuracy rates and the energy consumption values. The proposed architecture shows that cross-layer security integration can provide defense in depth while it still satisfies the constraints of resource-limited IoT environments. The discussion highlights open challenges and the future research directions for the IoT security architectures that include the post-quantum migration, secure federated model exchange and the automated compliance verification.
Many tracking companies collect user data and sell it to data markets and advertisers. While they claim to protect user privacy by anonymizing the data, our research reveals that significant privacy risks persist even with anonymized data. Attackers can exploit this data to identify users' accounts on other websites and perform targeted identity alignment. In this paper, we propose an effective identity alignment scheme for accurately identifying targeted users. We develop a data collector to obtain the necessary datasets, an algorithm for identity alignment, and, based on this, construct two types of de-anonymization attacks: the \textit{passive attack}, which analyzes tracker data to align identities, and the \textit{active attack}, which induces users to interact online, leading to higher success rates. Furthermore, we introduce, for the first time, a novel evaluation framework for online tracking-based identity alignment. We investigate the key factors influencing the effectiveness of identity alignment. Additionally, we provide an independent assessment of our generated dataset and present a fully functional system prototype applied to a cryptocurrency use case.
Cryptomining poses significant security risks, yet traditional detection methods like blacklists and Deep Packet Inspection (DPI) are often ineffective against encrypted mining traffic and suffer from high false positive rates. In this paper, we propose a practical encrypted cryptomining traffic detection mechanism. It consists of a two-stage detection framework, which can effectively provide fine-grained detection results by machine learning and reduce false positives from classifiers through active probing. Our system achieves an F1-score of 0.99 and identifies specific cryptocurrencies with a 99.39\% accuracy rate. Extensive testing across various mining pools confirms the effectiveness of our approach, offering a more precise and reliable solution for identifying cryptomining activities.
Shaoyu Li, Hexuan Yu, Shanghao Shi, Md Mohaimin Al Barat · 7 authors
With the growing demand for wireless spectrum, dynamic spectrum sharing (DSS) frameworks such as the Citizens Broadband Radio Service (CBRS) have emerged as practical solutions to improve utilization while protecting incumbent users (IUs) such as military radars. However, current incumbent protection mechanisms face critical limitations. The Environmental Sensing Capability (ESC) requires costly sensor deployments and remains vulnerable to interference and security risks. Alternatively, the Incumbent Informing Capability (IIC) requires IUs to disclose their identities and operational parameters to the Spectrum Coordination System (SCS), creating linkable records that compromise operational privacy and mission secrecy. We propose IU-GUARD, a privacy-preserving spectrum sharing framework that enables IUs to access spectrum without revealing their identities. Leveraging verifiable credentials (VCs) and zero-knowledge proofs (ZKPs), IU-GUARD allows IUs to prove their authorization to the SCS while disclosing only essential operational parameters. This decouples IU identity from spectrum access, prevents cross-request linkage, and mitigates the risk of centralized SCS data leakage. We implement a prototype, and our evaluation shows that IU-GUARD achieves strong privacy guarantees with practical computation and communication overhead, making it suitable for real-time DSS deployment.
Unlike Ethereum, which was conceived as a general-purpose smart-contract platform, Bitcoin was designed primarily as a transaction ledger for its native currency, which limits programmability for conditional applications. This constraint is particularly evident when considering oracles, mechanisms that enable Bitcoin contracts to depend on exogenous events. This paper investigates whether new oracle designs have emerged for Bitcoin Layer 1 since the 2015 transition to the Ethereum smart contracts era and whether subsequent Bitcoin improvement proposals have expanded oracles' implementability. Using Scopus and Web of Science searches, complemented by Google Scholar to capture protocol proposals, we observe that the indexed academic coverage remains limited, and many contributions circulate outside journal venues. Within the retrieved corpus, the main post-2015 shift is from multisig-style, which envisioned oracles as co-signers, toward attestation-based designs, mainly represented by Discreet Log Contracts (DLCs), which show stronger Bitcoin community compliance, tool support, and evidence of practical implementations in real-world scenarios such as betting and prediction-market mechanisms.
Protecting the intellectual property of large language models (LLMs) is a critical challenge due to the proliferation of unauthorized derivative models. We introduce a novel fingerprinting framework that leverages the behavioral patterns induced by safety alignment, applying the concept of refusal vectors for LLM provenance tracking. These vectors, extracted from directional patterns in a model's internal representations when processing harmful versus harmless prompts, serve as robust behavioral fingerprints. Our contribution lies in developing a fingerprinting system around this concept and conducting extensive validation of its effectiveness for IP protection. We demonstrate that these behavioral fingerprints are highly robust against common modifications, including finetunes, merges, and quantization. Our experiments show that the fingerprint is unique to each model family, with low cosine similarity between independently trained models. In a large-scale identification task across 76 offspring models, our method achieves 100\% accuracy in identifying the correct base model family. Furthermore, we analyze the fingerprint's behavior under alignment-breaking attacks, finding that while performance degrades significantly, detectable traces remain. Finally, we propose a theoretical framework to transform this private fingerprint into a publicly verifiable, privacy-preserving artifact using locality-sensitive hashing and zero-knowledge proofs.
This work presents a concept and implementation for the secure storage and transfer of quality-relevant data of milled workpieces from online-quality assurance processes enabled by real-time simulation models. It utilises Non-Fungible Tokens (NFT) to securely and interoperably store quality data in the form of an Asset Administration Shell (AAS) on a public Ethereum blockchain. Minted by a custom smart contract, the NFTs reference the metadata saved in the Interplanetary File System (IPFS), allowing new data from additional processing steps to be added in a flexible yet secure manner. The concept enables automated traceability throughout the value chain, minimising the need for time-consuming and costly repetitive manual quality checks.
Open access
3 source records
Digital Transformation in Industry
Blockchain Technology Applications and Security
Physical Unclonable Functions (PUFs) and Hardware Security
The rapid advancement of large language models (LLMs) demands increasingly reliable evaluation, yet current centralized evaluation suffers from opacity, overfitting, and hardware-induced variance. Our empirical analysis reveals an alarming inconsistency in existing evaluations: the standard deviation across ten repeated runs of a single model on HumanEval (1.67) actually exceeds the performance gap among the top-10 models on the official leaderboard (0.91), rendering current rankings statistically precarious. To mitigate these instabilities, we propose a decentralized evaluation framework that enables hardware and parameter diversity through large-scale benchmarking across heterogeneous compute nodes. By leveraging the blockchain-based protocol, the framework incentivizes global contributors to act as independent validators, using a robust reward system to ensure evaluation integrity and discourage dishonest participation. This collective verification transforms evaluation from a "centralized black box" into a "decentralized endorsement" where multi-party consensus and diverse inference environments yield a more stable, representative metric. Experimental results demonstrate that the decentralized evaluation framework reduces the standard deviation across ten runs on the same model to 0.28. This significant improvement over conventional frameworks ensures higher statistical confidence in model rankings. We have completely implemented this platform and will soon release it to the community.
A big challenge posed in blockchain centric platforms is achieving scalability while also preserving user privacy. This report details the design, implementation and evaluation of a Layer-2 scaling solution for Hyperledger Fabric using Zero Knowledge Rollups (ZK Rollups). The proposed architecture introduces an off chain sequencer that accepts transactions immediately and sends them for batching into a Merkle tree based rollup, using ZK proofs to attest to the correctness and verifiability of the entire batch. The design aims to decouple transaction ingestion from actual on chain settlements to address Fabric scalability limitations and increase throughput under high load conditions. The baseline architecture in Hyperledger Fabric constrains transaction requests due to endorsement, ordering and validation phases, leading to a throughput of 5 to 7 TPS with an average latency of 4 seconds. Our Layer-2 solution achieves an ingestion throughput of 70 to 100 TPS, leading to an increase of nearly ten times due to the sequencer immediate acceptance of each transaction and reducing client perceived latency by nearly eighty percent to 700 to 1000 milliseconds. This work demonstrates that integrating ZK Rollups in Hyperledger Fabric enhances scalability while not compromising the security guarantees of a permissioned blockchain network.
As artificial intelligence (AI) systems grow more powerful, autonomous, and embedded in critical infrastructure, their identification and traceability become foundational to regulatory oversight and sustainable digital governance. In digitally transformed enterprises, long-term sustainability depends on transparent, accountable, and lifecycle-governed AI systems, all of which require verifiable identity. This study proposes a conceptual and architectural framework for AI identification, combining technical and governance mechanisms to support lifecycle accountability. The framework integrates five components: model fingerprinting, cryptographic hashing, blockchain-based registration, zero-knowledge proof (ZKP)-based proof of possession, and post-deployment structural change screening. We introduce a dual-layer identifier, consisting of a machine-verifiable primary hash and a human-readable secondary identifier, anchored in a tamper-resistant registry. Identity validation is supported by selective ZKP-based verification at governance-defined checkpoints, while post-deployment changes are monitored using Lempel--Ziv Jaccard Distance (LZJD) as a governance-oriented screening signal rather than a semantic performance metric. The framework establishes an enforceable and transparent identity infrastructure that enables continuity, auditability, and policy-aligned oversight across AI system lifecycles. By embedding AI identification within enterprise architecture and governance processes, the proposed approach supports sustainable innovation, strengthens institutional accountability, and provides a foundation for selective, policy-defined verification during digital transformation.
This paper addresses the critical challenge of access control in modern supply chains, which operate across multiple independent and competing organizations. Existing access control is static and centralized, unable to adapt to insider threats or evolving contexts. Blockchain improves decentralization but lacks behavioral intelligence, while centralized machine learning for anomaly detection requires aggregating sensitive data, violating privacy. The proposed solution is ICBAC, an intelligent contract-based access control framework. It integrates permissioned blockchain (Hyperledger Fabric) with federated learning (FL). Built on Fabric, ICBAC uses a multi-channel architecture and three smart contracts for asset management, baseline access control, and dynamic revocation. To counter insider misuse, each channel deploys an AI agent that monitors activity and dynamically restricts access for anomalies. Federated learning allows these agents to collaboratively improve detection models without sharing raw data. For heterogeneous, competitive environments, ICBAC introduces a game-theoretic client selection mechanism using hedonic coalition formation. This enables supply chains to form stable, strategy-proof FL coalitions via preference-based selection without disclosing sensitive criteria. Extensive experiments on a Fabric testbed with a real-world dataset show ICBAC achieves blockchain performance comparable to static frameworks and provides effective anomaly detection under IID and non-IID data with zero raw-data sharing. ICBAC thus offers a practical, scalable solution for dynamic, privacy-preserving access control in decentralized supply chains.
Multi-implementation systems are increasingly audited against natural-language specifications. Differential testing scales well when implementations disagree, but it provides little signal when all implementations converge on the same incorrect interpretation of an ambiguous requirement. We present SPECA, a Specification-to-Checklist Auditing framework that turns normative requirements into checklists, maps them to implementation locations, and supports cross-implementation reuse. We instantiate SPECA in an in-the-wild security audit contest for the Ethereum Fusaka upgrade, covering 11 production clients. Across 54 submissions, 17 were judged valid by the contest organizers. Cross-implementation checks account for 76.5 percent (13 of 17) of valid findings, suggesting that checklist-derived one-to-many reuse is a practical scaling mechanism in multi-implementation audits. To understand false positives, we manually coded the 37 invalid submissions and find that threat model misalignment explains 56.8 percent (21 of 37): reports that rely on assumptions about trust boundaries or scope that contradict the audit's rules. We detected no High or Medium findings in the V1 deployment; misses concentrated in specification details and implicit assumptions (57.1 percent), timing and concurrency issues (28.6 percent), and external library dependencies (14.3 percent). Our improved agent, evaluated against the ground truth of a competitive audit, achieved a strict recall of 27.3 percent on high-impact vulnerabilities, placing it in the top 4 percent of human auditors and outperforming 49 of 51 contestants on critical issues. These results, though from a single deployment, suggest that early, explicit threat modeling is essential for reducing false positives and focusing agentic auditing effort. The agent-driven process enables expert validation and submission in about 40 minutes on average.
Zeta Avarikioti, Ray Neiheiser, Krzysztof Pietrzak, Michelle Yeo
Over the last years, Ethereum has evolved into a public platform that safeguards the savings of hundreds of millions of people and secures more than $650 billion in assets, placing it among the top 25 stock exchanges worldwide in market capitalization, ahead of Singapore, Mexico, and Thailand. As such, the performance and security of the Ethereum blockchain are not only of theoretical interest, but also carry significant global economic implications. At the time of writing, the Ethereum platform is collectively secured by almost one million validators highlighting its decentralized nature and underlining its economic security guarantees. However, due to this large validator set, the protocol takes around 15 minutes to finalize a block which is prohibitively slow for many real world applications. This delay is largely driven by the cost of aggregating and disseminating signatures across a validator set of this scale. Furthermore, as we show in this paper, the existing protocol that is used to aggregate and disseminate the signatures has several shortcomings that can be exploited by adversaries to shift stake proportion from honest to adversarial nodes. In this paper, we introduce Wonderboom, the first million scale aggregation protocol that can efficiently aggregate the signatures of millions of validators in a single Ethereum slot (x32 faster) while offering higher security guarantees than the state of the art protocol used in Ethereum. Furthermore, to evaluate Wonderboom, we implement the first simulation tool that can simulate such a protocol on the million scale and show that even in the worst case Wonderboom can aggregate and verify more than 2 million signatures within a single Ethereum slot.
Digital sovereignty has emerged as a central concern for modern software-intensive systems, driven by the dominance of non-sovereign cloud infrastructures, the rapid adoption of Generative AI, and increasingly stringent regulatory requirements. While existing initiatives address governance, compliance, and security in isolation, they provide limited guidance on how sovereignty can be operationalized at the architectural level. In this paper, we argue that sovereignty must be treated as a first-class architectural property rather than a purely regulatory objective. We introduce a Sovereign Reference Architecture that integrates self-sovereign identity, blockchain-based trust and auditability, sovereign data governance, and Generative AI deployed under explicit architectural control. The architecture explicitly captures the dual role of Generative AI as both a source of governance risk and an enabler of compliance, accountability, and continuous assurance when properly constrained. By framing sovereignty as an architectural quality attribute, our work bridges regulatory intent and concrete system design, offering a coherent foundation for building auditable, evolvable, and jurisdiction-aware AI-enabled systems. The proposed reference architecture provides a principled starting point for future research and practice at the intersection of software architecture, Generative AI, and digital sovereignty.
Despite the advantages of decentralization and immutability, blockchain technology faces significant scalability and throughput limitations, which has prompted the exploration of off-chain solutions like payment channels. Adaptor signatures have been considered a promising primitive for constructing such channels due to their support for atomicity, offering an alternative to traditional hash-timelock contracts. However, standard adaptor signatures may reveal signer identity, raising potential privacy concerns. While ring signatures can mitigate this issue by providing anonymity, they often introduce high communication overhead, particularly in multi-account payment settings commonly used in UTXO-based blockchains like Monero. To address these limitations, we propose a Linkable Threshold Ring Adaptor Signature (LTRAS) scheme, which integrates the conditional binding of adaptor signatures, the multi-account payment of threshold ring signatures, and the linkability for preventing double-spending. The formal definition, security model and concrete construction of LTRAS are provided. We also analyze its security and evaluate its performance through theoretical analysis and experimental implementation. Experimental results demonstrate that our scheme achieve significantly lower computation and communication overhead compared to existing schemes in large ring sizes and multi-account payment scenarios. Finally, we discuss its application in cross-chain atomic swaps, demonstrating its potential for enhancing privacy and efficiency in blockchain transactions.
The rapid advancement of generative AI systems has collapsed the credibility landscape for photographic evidence. Modern image generation models produce photorealistic images undermining the evidentiary foundation upon which journalism and public discourse depend. Existing authentication approaches, such as the Coalition for Content Provenance and Authenticity (C2PA), embed cryptographically signed metadata directly into image files but suffer from two critical failures: technical vulnerability to metadata stripping during social media reprocessing, and structural dependency on corporate-controlled verification infrastructure where commercial incentives may conflict with public interest. We present the Birthmark Standard, an authentication architecture leveraging manufacturing-unique sensor entropy from non-uniformity correction (NUC) maps and PRNU patterns to generate hardware-rooted authentication keys. During capture, cameras create anonymized authentication certificates proving sensor authenticity without exposing device identity via a key table architecture maintaining anonymity sets exceeding 1,000 devices. Authentication records are stored on a consortium blockchain operated by journalism organizations rather than commercial platforms, enabling verification that survives all metadata loss. We formally verify privacy properties using ProVerif, proving observational equivalence for Manufacturer Non-Correlation and Blockchain Observer Non-Identification under Dolev-Yao adversary assumptions. The architecture is validated through prototype implementation using Raspberry Pi 4 hardware, demonstrating the complete cryptographic pipeline. Performance analysis projects camera overhead below 100ms and verification latency below 500ms at scale of one million daily authentications.
Effective demand forecasting is crucial for reducing food waste. However, data privacy concerns often hinder collaboration among retailers, limiting the potential for improved predictive accuracy. In this study, we explore the application of Federated Learning (FL) in Sustainable Supply Chain Management (SSCM), with a focus on the grocery retail sector dealing with perishable goods. We develop a baseline predictive model for demand forecasting and waste assessment in an isolated retailer scenario. Subsequently, we introduce a Blockchain-based FL model, trained collaboratively across multiple retailers without direct data sharing. Our preliminary results show that FL models have performance almost equivalent to the ideal setting in which parties share data with each other, and are notably superior to models built by individual parties without sharing data, cutting waste and boosting efficiency.
Gradient boosted decision trees, particularly XGBoost, are among the most effective methods for tabular data. As deployment in sensitive settings increases, cryptographic guarantees of model integrity become essential. We present ZKBoost, the first zero-knowledge proof of training (zkPoT) protocol for XGBoost, enabling model owners to prove correct training on a committed dataset without revealing data or model parameters. Naively re-executing XGBoost training in ZK would incur prohibitive costs, primarily due to the oblivious partitioning of training samples and unknown tree splits. Moreover, previous work on ZKP of training and inference had subtle security issues, such as leakage of tree topology and soundness gaps allowing cheating model providers to deviate from the correct execution of training and inference. We make two key contributions to address these challenges: (1) a generic zkPoT template for XGBoost that can be instantiated with any general-purpose ZKP backend, significantly improving prover costs compared to naive re-execution of the training process; and (2) a VOLE-based instantiation that overcomes the security issues of previous ZK proofs of training at minimal costs. To maximize efficiency, we develop a fixed-point version of XGBoost, which is particularly well suited for efficient instantiation of ZKP, and show it matches standard XGBoost accuracy to within 1\% on real-world datasets.
Block space on the blockchain is scarce and must be allocated efficiently through block building. However, Ethereum's current block-building ecosystem, MEV-Boost, has become highly centralized due to integration, which distorts competition, reduces blockspace efficiency, and obscures MEV flow transparency. To guarantee equitability and economic efficiency in block building, we propose $\mathrm{Boost+}$, a system that decouples the process into collecting and ordering transactions, and ensures equal access to all collected transactions. The core of $\mathrm{Boost+}$ is the mechanism $\mathit{M}_{\mathrm{Boost+}}$, built around a default algorithm. $\mathit{M}_{\mathrm{Boost+}}$ aligns incentives for both searchers (intermediaries that generate or route transactions) and builders: Truthful bidding is a dominant strategy for all builders. For searchers, truthful reporting is dominant whenever the default algorithm dominates competing builders, and it remains dominant for all conflict-free transactions, even when builders may win. We further show that even if a searcher can technically integrate with a builder, non-integration combined with truthful bidding still dominates any deviation for conflict-free transactions. We also implement a concrete default algorithm informed by empirical analysis of real-world transactions and evaluate its efficacy using historical transaction data.
Large language models (LLMs) have been widely adopted in modern software development lifecycles, where they are increasingly used to automate and assist code generation, significantly improving developer productivity and reducing development time. In the blockchain domain, developers increasingly rely on LLMs to generate and maintain smart contracts, the immutable, self-executing components of decentralized applications. Because deployed smart contracts cannot be modified, correctness and security are paramount, particularly in high-stakes domains such as finance and governance. Despite this growing reliance, the security implications of LLM-generated smart contracts remain insufficiently understood. In this work, we conduct a systematic security analysis of Solidity smart contracts generated by state-of-the-art LLMs, including ChatGPT, Gemini, and Sonnet. We evaluate these contracts against a broad set of known smart contract vulnerabilities to assess their suitability for direct deployment in production environments. Our extensive experimental study shows that, despite their syntactic correctness and functional completeness, LLM-generated smart contracts frequently exhibit severe security flaws that could be exploited in real-world settings. We further analyze and categorize these vulnerabilities, identifying recurring weakness patterns across different models. Finally, we discuss practical countermeasures and development guidelines to help mitigate these risks, offering actionable insights for both developers and researchers. Our findings aim to support safe integration of LLMs into smart contract development workflows and to strengthen the overall security of the blockchain ecosystem against future security failures.
Jiaqi Gao, Zijian Zhang, Yuqiang Sun, Ye Liu · 8 authors
Business logic vulnerabilities have become one of the most damaging yet least understood classes of smart contract vulnerabilities. Unlike traditional bugs such as reentrancy or arithmetic errors, these vulnerabilities arise from missing or incorrectly enforced business invariants and are tightly coupled with protocol semantics. Existing static analysis techniques struggle to capture such high-level logic, while recent large language model based approaches often suffer from unstable outputs and low accuracy due to hallucination and limited verification. In this paper, we propose LogicScan, an automated contrastive auditing framework for detecting business logic vulnerabilities in smart contracts. The key insight behind LogicScan is that mature, widely deployed on-chain protocols implicitly encode well-tested and consensus-driven business invariants. LogicScan systematically mines these invariants from large-scale on-chain contracts and reuses them as reference constraints to audit target contracts. To achieve this, LogicScan introduces a Business Specification Language (BSL) to normalize diverse implementation patterns into structured, verifiable logic representations. It further combines noise-aware logic aggregation with contrastive auditing to identify missing or weakly enforced invariants while mitigating LLM-induced false positives. We evaluate LogicScan on three real-world datasets, including DeFiHacks, Web3Bugs, and a set of top-200 audited contracts. The results show that LogicScan achieves an F1 score of 85.2%, significantly outperforming state-of-the-art tools while maintaining a low false-positive rate on production-grade contracts. Additional experiments demonstrate that LogicScan maintains consistent performance across different LLMs and is cost-effective, and that its false-positive suppression mechanisms substantially improve robustness.
The rapid advancement of artificial intelligence has made the generation of synthetic images widely accessible, increasing concerns related to misinformation, digital forgery, and content authenticity on large-scale online platforms. This paper proposes a blockchain-backed framework for verifying AI-generated images through a registry-based provenance mechanism. Each AI-generated image is assigned a digital fingerprint that preserves similarity using perceptual hashing and is registered at creation time by participating generation platforms. The hashes are stored on a hybrid on-chain/off-chain public blockchain using a Merkle Patricia Trie for tamper-resistant storage (on-chain) and a Burkhard-Keller tree (off-chain) to enable efficient similarity search over large image registries. Verification is performed when images are re-uploaded to digital platforms such as social media services, enabling identification of previously registered AI-generated images even after benign transformations or partial modifications. The proposed system does not aim to universally detect all synthetic images, but instead focuses on verifying the provenance of AI-generated content that has been registered at creation time. By design, this approach complements existing watermarking and learning-based detection methods, providing a platform-agnostic, tamper-proof mechanism for scalable content provenance and authenticity verification at the point of large-scale online distribution.
The digitization of healthcare has generated massive volumes of Electronic Health Records (EHRs), offering unprecedented opportunities for training Artificial Intelligence (AI) models. However, stringent privacy regulations such as GDPR and HIPAA have created data silos that prevent centralized training. Federated Learning (FL) has emerged as a promising solution that enables collaborative model training without sharing raw patient data. Despite its potential, FL remains vulnerable to poisoning and Sybil attacks, in which malicious participants corrupt the global model or infiltrate the network using fake identities. While recent approaches integrate Blockchain technology for auditability, they predominantly rely on probabilistic reputation systems rather than robust cryptographic identity verification. This paper proposes a Trustworthy Blockchain-based Federated Learning (TBFL) framework integrating Self-Sovereign Identity (SSI) standards. By leveraging Decentralized Identifiers (DIDs) and Verifiable Credentials (VCs), our architecture ensures only authenticated healthcare entities contribute to the global model. Through comprehensive evaluation using the MIMIC-IV dataset, we demonstrate that anchoring trust in cryptographic identity verification rather than behavioral patterns significantly mitigates security risks while maintaining clinical utility. Our results show the framework successfully neutralizes 100% of Sybil attacks, achieves robust predictive performance (AUC = 0.954, Recall = 0.890), and introduces negligible computational overhead (<0.12%). The approach provides a secure, scalable, and economically viable ecosystem for inter-institutional health data collaboration, with total operational costs of approximately $18 for 100 training rounds across multiple institutions.
Consent is an ethical cornerstone of clinical research and healthcare in general. Although the ethical principles of consent - providing information, ensuring comprehension, and ensuring voluntariness - are well-defined, the technological infrastructure remains outdated. Clinicians are responsible for obtaining informed consent from research subjects or patients, and for managing it before, during, and after clinical trials or care, which is a burden for them. The voluntary nature of participating in clinical research or undergoing medical treatment implies the need for a participant-centric consent management system. However, this is not reflected in most established systems. Not only do most healthcare information systems not follow a user-centric model, but they also create data silos, which significantly reduce the mobility of patient data between different healthcare institutions and impact personalized medicine. Furthermore, consent management tools are outdated. We propose ClinConNet (Clinical Consent Network), a platform that connects researchers and participants based on clinical research projects. ClinConNet is powered by a dynamic consent model based on blockchain and take advantage of dynamic consent interfaces, as well as blockchain and Self-Sovereign Identity systems. ClinConNet is user-centric and provides important privacy features for patients, such as unlinkability, confidentiality, and ownership of identity data. It is also compatible with the right to be forgotten, as defined in many personal data protection regulations, such as the GDPR. We provide a detailed privacy and security analysis in an adversarial model, as well as a Proof of Concept implementation with detailed performance measures that demonstrate the feasibility of our blockchain-based consent management system with a median end-to-end consent establishment time of under 200ms and a throughput of 250TPS.