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June 27, 2025· Zenodo (CERN European Organization for Nuclear Research)
article
Open access

The Immutable Health Ledger: A Zero-Trust, Post-Quantum Blueprint for Biometric-Sealed Patient Data Sovereignty

Abstract

This paper introduces a comprehensive architectural framework for quantum-resistant health data management. The proposed Immutable Health Ledger (IHL) represents a fundamental paradigm shift an advanced Zero-Trust architecture engineered to withstand both current cyber threats and the emerging challenges posed by quantum computing, which are expected to render existing encryption standards obsolete. The IHL ensures provable data sovereignty through three foundational principles: a Biometric Trust Anchor in which patient identity serves as the cryptographic root of trust; a Post-Quantum Cryptographic Foundation built upon NIST-standardized algorithms with a hybrid deployment strategy; and a Distributed Integrity Layer that makes any form of data manipulation computationally and economically impractical. This document presents the complete mathematical formulations, formal security proofs, performance analyses, and an implementation roadmap that together define the operational and theoretical integrity of the proposed system.

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