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July 30, 2026· Zenodo (CERN European Organization for Nuclear Research)
article
Open access

Blockchain-Enabled Drug Supply Chain for Secure Pharmaceutical Tracking

Authors:Pratham PujariDr. Shravankumar Arjunagi

Abstract

Counterfeit medicines, fragmented record management, limited end-to-end visibility, and dependence on centralized databases create security and traceability challenges in pharmaceutical supply chains. This article presents Pharma-Chain, a blockchain-enabled pharmaceutical supply chain management system developed to record medicine registration, stakeholder interactions, ownership transfer, and authenticity verification on an Ethereum blockchain. The system integrates a React.js frontend with Web3.js, MetaMask wallet authentication, Solidity smart contracts, Truffle deployment tools, and Ganache for local blockchain development and validation. Manufacturers register medicine batches with product and lifecycle information; distributors and retailers verify blockchain records before accepting and transferring ownership; and customers retrieve medicine details and transaction history before purchase. The implementation was tested module by module and as an integrated application in a local Ethereum environment. Testing confirmed successful authentication and role-based access, medicine registration, ownership transfer, transaction validation, blockchain record retrieval, and medicine verification. Each successful supply-chain operation generated a blockchain transaction record, providing an immutable ownership history and improving transparency and auditability. The project demonstrates a practical decentralized approach for secure pharmaceutical tracking while identifying QR-code verification, IoT monitoring, AI-assisted analytics, mobile access, and deployment on public or enterprise blockchain networks as future extensions.

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