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April 2, 2026· IEEE Transactions on Big Data
article

PureRx: A Non-Fungible Token-Based Prescription Management for Efficient and Secure Healthcare System

Authors:Gifar Arif HaryadiAllwinnaldoMuhammad Rasyid Redha AnsoriJae-Min LeeDong-Seong Kim

Abstract

PureRx is an innovative blockchain-based prescription management system designed to overcome the limitations of traditional paper prescriptions, including medication errors, fraud, and inefficiencies in tracking patient records. By leveraging Non-Fungible Tokens (NFTs) and batch minting, PureRx enables efficient, secure, and patient-centric control of prescription data. Patients maintain ownership of their medical records, while healthcare providers and pharmacies benefit from transparent and immutable prescription workflows. Experimental evaluation shows that PureRx improves operational efficiency by 37.18% in initial cycles, increasing to 51% in subsequent cycles compared to existing systems, while reducing costs by 46.76% in high-volume scenarios. Security analysis confirmed that no critical vulnerabilities were found and that all prescription issuance and claiming events are tamper-resistant and auditable on-chain. By combining scalability, transparency, and patient empowerment, PureRx demonstrates the potential of blockchain to transform prescription management in modern healthcare systems.

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