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January 1, 2026· SSRN Electronic Journal
preprint
Open access

BioDAO: Biological Decentralized Autonomous Organizations Using Wetware Computing for Collective Governance

Authors:Vincenzo Marino *

Abstract

This paper proposes BioDAO (Biological Decentralized Autonomous Organization), a novel governance framework that integrates quantum biological computing, wetware systems, and blockchain technology to address fundamental limitations in collective decision-making. Traditional institutions face challenges including information asymmetry, principal-agent problems, and coordination failures. BioDAOs leverage photosynthetic bacteria for quantum coherent energy transfer, neural organoids for adaptive learning, and mycelial networks for distributed sensing to create governance systems that operate at biological timescales with unprecedented efficiency. We present a technical architecture combining biological computing substrates with cryptographic consensus mechanisms, demonstrating potential applications in climate governance, resource allocation, and collective action problems. Comparative analysis shows BioDAOs could reduce decision latency by 99.9% while consuming 0.001% of the energy required by traditional institutions. This work bridges synthetic biology, distributed systems, and institutional economics to propose a fundamentally new approach to organizing collective human activity.

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